| First Author | Burbassi S | Year | 2010 |
| Journal | Eur J Neurosci | Volume | 32 |
| Issue | 8 | Pages | 1278-88 |
| PubMed ID | 20880358 | Mgi Jnum | J:169500 |
| Mgi Id | MGI:4941115 | Doi | 10.1111/j.1460-9568.2010.07402.x |
| Citation | Burbassi S, et al. (2010) Alterations of CXCR4 function in mu-opioid receptor-deficient glia. Eur J Neurosci 32(8):1278-88 |
| abstractText | The chemokine receptor CXCR4 and the mu-opioid receptor (MOR) are G-protein-coupled receptors that are essential for normal function of the nervous and immune systems. Several studies have suggested that MOR is a key regulator of CXCR4 in the brain; however, the molecular basis of the opioid-chemokine interaction is not fully understood, and it may involve different mechanisms in neuronal and glial cells. Our previous studies demonstrated that MOR stimulation specifically upregulates the protein ferritin heavy chain - an inhibitor of CXCR4 |
