Primary Identifier | MGI:2176270 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pou4f3 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
description | Homozygous mutant mice have a similar phenotype to dreidel mice, which are homozygous for Pou4f3ddl. Phenotypic Similarity to Human Syndrome: Hereditary Deafness J:207266. |
molecularNote | A neomycin selection cassette replaced a 2.4 kb genomic fragment containing the entire coding sequence of the gene. In situ hybridization analysis confirmed absence of mRNA in trigeminal ganglia of mutant mice. |