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Allele : Mb<tm1Wlm> myoglobin; targeted mutation 1, R Saunders Williams

Primary Identifier  MGI:2159349 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mb
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette replaced a genomic fragment containing exon 2, which encodes the haem-binding domain. RT-PCR analysis on RNA derived from hearts of homozygous mice demonstrated that no detectable transcript was produced from this allele. Western blot and immunohistochemical analyses confirmed that no stable protein was made from this allele in cardiac tissue of homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Mb<->,
  • myoglobin -,
  • Mb<->,
  • myoglobin -
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories

Trail: Allele