Primary Identifier | MGI:2159355 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Gpc3 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin selection cassette replaced genomic sequences corresponding to the transcriptional and translational start sites, and encoding the signal peptide and first 33 amino acids of the mature protein. Western blot analysis on purified proteoglycan extracts derived from E16.5 liver of male hemizygous mice confirmed that no detectable protein is produced from this allele. |