| First Author | Stanley EG | Year | 2000 |
| Journal | Genesis | Volume | 26 |
| Issue | 4 | Pages | 259-64 |
| PubMed ID | 10748464 | Mgi Jnum | J:62081 |
| Mgi Id | MGI:1858314 | Doi | 10.1002/(sici)1526-968x(200004)26:4<259::aid-gene70>3.0.co;2-v |
| Citation | Stanley EG, et al. (2000) Targeted insertion of a lacZ reporter gene into the mouse Cer1 locus reveals complex and dynamic expression during embryogenesis [letter]. Genesis 26(4):259-64 |
| abstractText | The mouse Cer1 (mCer1, Cer-l, Cerr1) gene encodes one member of a family of cytokines structurally and functionally related to the Xenopus head-inducing factor, Cerberus (xCer). We generated a mouse line in which the Cer1 gene was inactivated by replacing the first coding exon with a lacZ reporter gene. Mice homozygous for this allele (Cer1(lacZ)) showed no apparent perturbation of embryogenesis or later development. However, the lacZ reporter revealed a number of hitherto uncharacterised sites of Cer1 expression in late fetal and adult tissues. Preliminary analysis suggests that Cer1 is not essential for their morphogenesis, differentiation, or homeostasis. PMID- 0010748464 PID - 10.1002/(SICI)1526-968X(200004)26:4<259::AID-GENE70>3.0.CO;2-V PST - ppublish MHDA- 2000/06/24 11:00 EDAT- 2000/04/05 09:00 |
