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Allele : Marcks<tm1Pjb> myristoylated alanine rich protein kinase C substrate; targeted mutation 1, Perry J Blackshear

Primary Identifier  MGI:2176302 Allele Type  Targeted
Attribute String  Null/knockout Gene  Marcks
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene was inserted into exon 1, 18 bp after the ATG initiation codon. Northern blot analysis on RNA derived from E18.5 embryonic heads of homozygous mice demonstrated that no detectable transcript was produced from this allele. Western blot analysis on on lysates also of E18.5 embryonic heads of homozygous mice confirmed that no detectable protein was expressed from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • MARCKS<->,
  • MARCKS<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

18 Publication categories

Trail: Allele