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Allele : Lepr<tm1Rck> leptin receptor; targeted mutation 1, Jeffrey M Friedman

Primary Identifier  MGI:2176774 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Lepr
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  A single loxP site was inserted 5' to exon 1 and a loxP-flanked neomycin and thymidine kinase selection cassette was inserted 3' to exon 1. The selection cassette was removed in ES cells by transient Cre expression prior to the production of chimeric mice. leaving a single loxP site 3' to exon 1 in the final allele.
  • mutations:
  • Insertion
  • synonyms:
  • ObR<flox>,
  • ObR<flox>,
  • LepR<fl>,
  • LepR<fl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

55 Publication categories

Trail: Allele