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Allele : Runx2<tm1Kish> runt related transcription factor 2; targeted mutation 1, Tadamitsu Kishimoto

Primary Identifier  MGI:2176466 Allele Type  Targeted
Attribute String  Null/knockout Gene  Runx2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neomycin resistance cassette replaced 1.2 kb of exon 1, which encodes the first 41 amino acids of the runt domain. RT-PCR analysis of the runt region did not detect cDNA in liver from homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Runx2<->,
  • Runx2<tm1Tki>,
  • Runx2<tm1Tki>,
  • Runx2-deltaC,
  • Cbfa1-,
  • Cbfa1-,
  • Runx2<->,
  • Runx2-deltaC
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

43 Publication categories

Trail: Allele