Primary Identifier | MGI:2176466 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Runx2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A PGK-neomycin resistance cassette replaced 1.2 kb of exon 1, which encodes the first 41 amino acids of the runt domain. RT-PCR analysis of the runt region did not detect cDNA in liver from homozygous mice. |