| Primary Identifier | MGI:2177611 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Gabra1 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A point mutation was introduced that altered codon 101 from one encoding histidine to one encoding arginine (H101R). This alteration had been shown to render the GABA-A receptor insensitive to drugs such as diazepam. A loxP flanked neomycin selection cassette was also inserted into an adjacent intron, but was removed by Cre mediated recombination in the final allele. |
