| Primary Identifier | MGI:2176758 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Casr |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance gene was inserted into exon 4. Western blot analysis on kidney protein membrane extracts from homozygous mice confirmed that no detectable protein is expressed from this allele. RT-PCR analysis of chondrocytes from homozygous mice detected the presence of a smaller transcript lacking exon 5. In addition protein expression is detected in the growth plates of homozygous mice. |
