| First Author | Zha C | Year | 2020 |
| Journal | bioRxiv | Mgi Jnum | J:292541 |
| Mgi Id | MGI:6450513 | Doi | 10.1101/763888 |
| Citation | Zha C, et al. (2020) MRI of Capn15 knockout mice and analysis of Capn15 distribution reveal possible roles in brain development and plasticity. bioRxiv |
| abstractText | The non-classical Small Optic Lobe (SOL) family of calpains are intracellular cysteine proteases that are expressed in the nervous system and appear to play an important role in neuronal development in both Drosophila, where loss of this calpain leads to the eponymous small optic lobes, and in mouse and human, where loss of this calpain (Capn15) leads to eye anomalies. However, the brain regions where this calpain is expressed and the areas most affected by the loss of this calpain have not been carefully examined. |
