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Allele : Fus<tm1(DDIT3)Dron> fused in sarcoma; targeted mutation 1, David Ron

Primary Identifier  MGI:2177655 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Fus
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A knock-in cassette containing a loxP-flanked neomycin gene followed by a human DDIT3 gene replaced exons 8 and 9. This allele expresses a fusion protein of FUS and Neo in which the neomycin sequences replace the RNA-binding C-terminal portion of the gene; the inserted DDIT3 gene is not expressed.
  • mutations:
  • Insertion
  • synonyms:
  • TLS -,
  • TLS-NEO,
  • Tls.m2,
  • Tls.m2,
  • TLS-NEO,
  • TLS -
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele