Primary Identifier | MGI:3583918 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ipmk |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 4, encoding the critical kinase motif DVKIG and residues critical to protein folding, was replaced with a neomycin resistance cassette via homologous recombination. In situ hybridization experiments indicated that no detectable transcript was expressed from this allele. |