| Primary Identifier | MGI:2177561 | Allele Type | Gene trapped |
| Attribute String | Null/knockout, Reporter | Gene | Fus |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The mutation was generated by the random insertion of the gene trap vector U3NeoSV1 into exon 12 of the gene. RT-PCR and Northern blot analysis demonstrated that a truncated transcript is produced from this allele, and western blot analysis confirmed that low levels of a truncated protein were expressed from this allele. However, the expressed product is not expected to retain activity due to missing nucleic acid binding domains. |
