Primary Identifier | MGI:2177773 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Srebf1 |
Transmission | Germline | Strain of Origin | 129S/SvEv |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = JH1 (129S7/SvEvBrd) or SM1 (129S6/SvEvTac). |
molecularNote | A neomycin resistance cassette was inserted into the middle of exon 2. Western blot analysis on membrane and nuclear extracts of liver from homozygous mice confirmed that no detectable protein was expressed from this allele. |