First Author | Kelaï S | Year | 2003 |
Journal | Alcohol Alcohol | Volume | 38 |
Issue | 4 | Pages | 386-9 |
PubMed ID | 12814910 | Mgi Jnum | J:101997 |
Mgi Id | MGI:3606379 | Doi | 10.1093/alcalc/agg095 |
Citation | Kelai S, et al. (2003) Alcohol intake after serotonin transporter inactivation in mice. Alcohol Alcohol 38(4):386-9 |
abstractText | Knock-out mice lacking the serotonin transporter [5-hydroxytryptamine transporter (5-HTT)] were used to assess the influence of 5-HT re-uptake on ethanol consumption. Under a free-choice paradigm, alcohol intake was lower in mutant than in wild-type mice, and pharmacological blockade of 5-HTT by fluoxetine reduced alcohol intake in wild-type mice only. These data confirm the inhibitory effect of 5-HTT inactivation on ethanol intake. |