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Allele : Adra2a<tm1Bkk> adrenergic receptor, alpha 2a; targeted mutation 1, Brian K Kobilka

Primary Identifier  MGI:2179108 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adra2a
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin cassette inserted into the gene by homologous recombination resulted in a premature stop codon within the third transmembrane domain. Confirmation of the targeting event was demonstrated through Southern analysis.
  • mutations:
  • Insertion
  • synonyms:
  • alpha2A-KO,
  • alpha2A-ARKO,
  • alpha2A-AR<->,
  • alpha2A-,
  • alpha2A-KO,
  • alpha2A-AR<->,
  • alpha2A-,
  • alpha2A-ARKO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

61 Publication categories

Trail: Allele