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Allele : Srebf1<tm2Jdh> sterol regulatory element binding transcription factor 1; targeted mutation 2, Jay D Horton

Primary Identifier  MGI:2177958 Allele Type  Targeted
Attribute String  Null/knockout Gene  Srebf1
Transmission  Germline Strain of Origin  129S/SvEv
Is Recombinase  false Is Wild Type  false
description  ES cell line = JH1 (129S7/SvEvBrd) or SM1 (129S6/SvEvTac).
molecularNote  A neomycin resistance cassette replaced a genomic fragment extending from the middle of exon 5 through exon 11. Western blot analysis on membrane and nuclear extracts of liver from homozygous mice demonstrated that a truncated protein was expressed from this allele that lacked the DNA-binding domains.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • allele B,
  • allele B
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

8 Publication categories

Trail: Allele