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Allele : Adarb1<tm1Phs> adenosine deaminase, RNA-specific, B1; targeted mutation 1, Peter H Seeburg

Primary Identifier  MGI:2178079 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adarb1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A PGK-neomycin resistance gene replaced most of exon 4, which encodes domains essential for protein function. RNase protection assays demonstrated that a mutant transcript was produced from this allele at low levels that may express a functionally inactive protein with intact RNA binding domains.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • ADAR2 -,
  • ADAR2 -
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

22 Publication categories

Trail: Allele