| Primary Identifier | MGI:2178586 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hells |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 6 and 7, containing a helicase domain (ATPase), and a DExH box, were relaced with a PGK-neo cassette. Successful targeting was confirmed by Southern analysis and PCR. Western analysis failed to detect protein from embryonic liver extracts in homozygous mutant animals. |