Primary Identifier | MGI:2179196 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lig1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The 3' end of the gene (exons 23-27) has been replaced with an HPRT minigene. In this allele, the more highly expressed DWM110 minigene was utilized. RT-PCR detected levels of Lig1-Hprt fusion transcripts although no protein product was detected by Western analysis. |