| Primary Identifier | MGI:2179201 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Top2b |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Two exons of the endogenous locus, one of which contains the active-site tyrosine codon, were replaced by a neo cassette. No transcript was detected from the liver of E18.5 mutant embryos. No protein was detected in extracts from fibroblasts of E13.5 mutant embryos. |
