| Primary Identifier | MGI:2178747 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Otx2 |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The promoter and first exon of the gene were flanked with inserted loxP sites. In addition, an frt-flanked neomycin resistance cassette was inserted into first intron. RT-PCR analysis on RNA derived from homozygous embryos demonstrated that aberrant neo-fusion transcripts were produced from this allele in addition to reduced levels of normal mRNA. |
