Primary Identifier | MGI:2179439 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cyp19a1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | 87 nucleotides of exon 9 were replaced with a neomycin resistance gene via homologous recombination. Northern blot of gene transcripts from ovaries of homozygous mutant animals verified the absence of exon 9 and enzyme assay detected negligible levels of enzyme activity. |