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Allele : Kcnj8<tm1Sse> potassium inwardly-rectifying channel, subfamily J, member 8; targeted mutation 1, Susumu Seino

Primary Identifier  MGI:2180015 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kcnj8
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Part of intron 2 and exon 3, which encode the pore-forming region of the ion channel, were replaced with a neomycin resistance cassette via homologous recombination. Lack of gene expression in brain, heart, and liver of homozygous mutant animals was confirmed via Northern blot analysis.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Kir6.1-null,
  • Kir6.1-null
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

15 Publication categories

Trail: Allele