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Allele : Tfap2b<tm1Rbu> transcription factor AP-2 beta; targeted mutation 1, Reinhard Buettner

Primary Identifier  MGI:2180473 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tfap2b
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The insertion of a PGK-neo cassette disrupted exon 4, which encodes an essential DNA binding domain. Northern blot and Western blot analyses showed an absence of transcript and protein, respectively, in midbrain lysates obtained from homozygous mutant mice.
  • mutations:
  • Insertion
  • synonyms:
  • Tcfap2b<tm1Rbu>,
  • Tcfap2b<tm1Rbu>,
  • AP-2Beta<->,
  • AP-2Beta<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

18 Publication categories

Trail: Allele