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Allele : Scnn1b<tm1Ipt> sodium channel, nonvoltage-gated 1 beta; targeted mutation 1, Edith Hummler

Primary Identifier  MGI:2179831 Allele Type  Targeted
Attribute String  Hypomorph Gene  Scnn1b
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  A stop codon followed by a loxP-flanked neomycin resistance cassette was inserted at a position corresponding to residue arg566 in the human gene. Northern blot analysis on colon, kidney and lung RNA revealed that a low level (1-4%) of a truncated transcript was expressed from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • betaENaC m/m,
  • betaENaC m/m
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

15 Publication categories

Trail: Allele