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Allele : Ache<tm1Loc> acetylcholinesterase; targeted mutation 1, Oksana Lockridge

Primary Identifier  MGI:2179948 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ache
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 5 kb genomic fragment containing exons 2-5 was replaced by a neomycin resistance gene cassette. Enzymatic activity assays on blood serum derived from homozygous mice confirmed that no functional protein was made from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • AChE-,
  • AChE ko,
  • AChE-,
  • AChE ko
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

27 Publication categories

Trail: Allele