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Allele : Grap2<tm1Amch> GRB2-related adaptor protein 2; targeted mutation 1, Alec M Cheng

Primary Identifier  MGI:2180009 Allele Type  Targeted
Attribute String  Null/knockout Gene  Grap2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Four exons encoding the C-terminal portion of the SH2 domain, the linker region, and the C-terminal SH3 domain were replaced with a neomycin cassette via homologous recombination. Protein product is absent in spleen from homozygous mutant animals as determined by Western blot analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • GADS-,
  • GADS-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories

Trail: Allele