Primary Identifier | MGI:2180009 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Grap2 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Four exons encoding the C-terminal portion of the SH2 domain, the linker region, and the C-terminal SH3 domain were replaced with a neomycin cassette via homologous recombination. Protein product is absent in spleen from homozygous mutant animals as determined by Western blot analysis. |