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Allele : Ap1m1<tm1Schu> adaptor-related protein complex AP-1, mu subunit 1; targeted mutation 1, Peter Schu

Primary Identifier  MGI:2180171 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ap1m1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted to disrupt an exon of the mu-adaptin gene. Northern analysis of total RNA isolated from homozygous embryos revealed an absence of transcript. Western analysis of homozygous mutants showed a 30% reduction in gamma-adaptin and a 70% reduction in sigma1-adaptin relative to a control.
  • mutations:
  • Insertion
  • synonyms:
  • delta-mu-1,
  • delta-mu-1
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele