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Allele : Sgcd<tm1Mcn> sarcoglycan, delta (dystrophin-associated glycoprotein); targeted mutation 1, Elizabeth M McNally

Primary Identifier  MGI:2180193 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sgcd
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was used to replace exon 2, which encodes the translation initiation codon and the cytoplasmic and transmembrane domains. Northern analysis showed that message was not transcribed in skeletal muscle of homozygous mutant mice. The lack of protein in immunoblots further confirmed complete inactivation.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Scgd<->,
  • Scgd<->,
  • dsg<->,
  • dsg<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

47 Publication categories

Trail: Allele