Primary Identifier | MGI:2180543 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Cask |
Strain of Origin | (C57BL/6J x DBA/2J)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A transgene containing the BNLF-1 gene of the Epstein Barr Virus inserted into an intron of the Cask gene. The intron separates the exons encoding the calmodulin binding domain, a domain common to both isoforms of this gene. The open reading frame was unaffected by the introduction, allowing for the possibility of a hybrid protein. It is unknown whether the resulting phenotype results from a gain of function or loss of function mutation. |