Primary Identifier | MGI:2181194 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Csf1r |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 3 was disrupted by the insertion of an in-frame cassette containing a humanized green fluorescent protein sequence and a neomycin resistance gene. While annulment of the allele in mutant mice was indicated by Western blot analysis of bone-marrow derived macrophages, expression of the green fluorescent protein could not be detected by fluorescence microscopy or flow cytometry. |