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Allele : Cldn11<tm1Ral> claudin 11; targeted mutation 1, Robert A Lazzarini

Primary Identifier  MGI:2181029 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Cldn11
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A construct containing a promoterless lacZ gene and a floxed PGK-neomycin resistance gene replaced exon 1 and a portion of intron 1. Northern blot analysis of extracts from brains and testes showed a lack of transcript in homozygous mutant mice. Western blot analysis confirmed an absence of encoded protein in brain homogenates. Expression of the inserted lacZ gene was under the control of the endogenous promoter.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • OSP/claudin-11 (-),
  • OSP/claudin-11 (-)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories

Trail: Allele