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Allele : Phlda2<tm2Bty> pleckstrin homology like domain, family A, member 2; targeted mutation 2, Benjamin Tycko

Primary Identifier  MGI:2181543 Allele Type  Targeted
Attribute String  Null/knockout Gene  Phlda2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Homologous recombination introduced loxP sites flanking the 2 exons of the gene. Mice carrying the targeted mutation were bred to the HSP-cre deleter strain resulting in deletion of the 2 exons and of half of the 5' upstream CpG islands. Absence of gene expression in yolk sacs of homozygous mutant embryos was demonstrated by Northern blot analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ipl<loxP>,
  • Ipl<loxP>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

7 Publication categories

Trail: Allele