Primary Identifier | MGI:2180816 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pcca |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neo cassette was used to replace ~ 2 kb of the gene, which contains exons that encode the N-terminal region of the protein. Northern analysis failed to detect transcript and there was an absence of enzymatic activity in homozygous mutant animals. |