Primary Identifier | MGI:2181292 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd44 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The 3' portion of exon 2 and all of exon 3 were replaced by the insertion of a neomycin resistance cassette. The deleted region encodes part of the invariant amino terminus, common to all isoforms. A lack of protein surface expression was observed in spleen, lymph node, and thymus cells via flow cytometry. |