| First Author | Maruyama K | Year | 2007 |
| Journal | Infect Immun | Volume | 75 |
| Issue | 3 | Pages | 1520-3 |
| PubMed ID | 17178788 | Mgi Jnum | J:118693 |
| Mgi Id | MGI:3700113 | Doi | 10.1128/IAI.01316-06 |
| Citation | Maruyama K, et al. (2007) c-Fos-deficient mice are susceptible to Salmonella enterica serovar Typhimurium infection. Infect Immun 75(3):1520-3 |
| abstractText | c-Fos is a component of transcription factor AP-1. We show that macrophages lacking c-Fos exhibit enhanced production of proinflammatory cytokines, potentiated NF-kappaB phosphorylation, and increased cell death following Salmonella enterica serovar Typhimurium infection. Furthermore, mice lacking c-Fos are highly susceptible to infection, suggesting that c-Fos confers resistance to Salmonella infection in mice. |
