| Primary Identifier | MGI:2181999 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Lhcgr |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 11, which encodes the transmembrane and cytoplasmic receptor domains, was replaced with a neomycin selection gene by homologous recombination. RT-PCR analysis demonstrated that no full length transcript was made in homozygous mice. Radioimmunoassays confirmed that no functional protein was present in homozygous mice. |
