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Allele : Dnmt3a<tm2Enl> DNA methyltransferase 3A; targeted mutation 2, En Li

Primary Identifier  MGI:2182412 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dnmt3a
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Targeting took place in ES cells heterozygous for Dnmt3atm1Enl, originally for the purpose of generating ES cells with both copies of the gene inactivated. A 0.3kb region of the wild-type allele encoding the PC and ENV motifs was replaced with a hygromycin selection cassette via homologous recombination.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

13 Publication categories

Trail: Allele