| Primary Identifier | MGI:2182589 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Fes |
| Transmission | Chimeric | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 2.5 kb region of the gene spanning exons 12-14 were replaced with a PGK-neo cassette via homologous recombination. The gene targeting event results in deletion of the C-terminal SH2 domain and the ATP-binding site of the tyrosine kinase domain (amino acids 497-607). Homozygous mutant embryonic stem cells were identified via Southern blot analysis. |
