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Allele : Gfap<tm1Ito> glial fibrillary acidic protein; targeted mutation 1, Shigeyoshi Itohara

Primary Identifier  MGI:2183216 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Gfap
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette, containing a promoterless lacZ and neo, was inserted immediately downstream of the endogenous start codon. Western blot analysis of protein extracts obtained from cerebrum, cerebellum, and spinal cord tissue showed an absence of encoded protein in homozygous mutant mice. The expression pattern of beta-galactosidase showed a strong correlation to that of the endogenous gene.
  • mutations:
  • Insertion
  • synonyms:
  • Gfap<->,
  • Gfap<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele