|  Help  |  About  |  Contact Us

Publication : Increased susceptibility of secretor factor gene Fut2-null mice to experimental vaginal candidiasis.

First Author  Hurd EA Year  2004
Journal  Infect Immun Volume  72
Issue  7 Pages  4279-81
PubMed ID  15213174 Mgi Jnum  J:90993
Mgi Id  MGI:3045646 Doi  10.1128/IAI.72.7.4279-4281.2004
Citation  Hurd EA, et al. (2004) Increased susceptibility of secretor factor gene Fut2-null mice to experimental vaginal candidiasis. Infect Immun 72(7):4279-81
abstractText  Fut2-LacZ-null mice, which are a model of the human ABO and Lewis nonsecretor group, display increased susceptibility to experimental yeast vaginitis, indicating a role for alpha(1,2)fucosylated cervical glycans in mucosal defense. However, the lack of significant effect of competitive inhibition by exogenous neoglycoproteins in this study emphasizes the complexity of Candida-epithelial cell adhesion events.
Quick Links:
 
Quick Links:
 

Expression

Publication --> Expression annotations

 

Other

2 Authors

6 Bio Entities

Trail: Publication

0 Expression