| Primary Identifier | MGI:2182739 | Allele Type | Chemically induced (ENU) |
| Attribute String | Hypomorph | Gene | G6pdx |
| Strain of Origin | 102/El | Is Recombinase | false |
| Is Wild Type | false |
| description | The original mutant was an offspring of a (102/El x C3H/El)F1 male that had received 250 mg/kg ENU mated to a tester stock female. Therefore, the mutation arose on a 102/El X Chromosome. |
| molecularNote | The mutation is an A to T transversion in the 5' splice site consensus sequence at the 3' terminal of exon 1. Decreased protein levels were determined in homozygous mutant mice via Western blot analysis. This is a hypomorphic allele; in hemizygous males, heterozygous females, and homozygous females, the activity level in blood is 20%, 60%, and 15% of normal, respectively. |
