| Primary Identifier | MGI:2183261 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Clcn2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A portion of exon 3 and all of exons 4 through 7 were replaced with a neomycin selection cassette. The deleted region encoded transmembrane domains 2 through 6. Truncated transcript was detected by Northern blot analysis using 5' and neo probes and undetected using a 3' probe. Protein was shown to be absent in homozygous mutant mice via Western blot analysis. |
