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Allele : Tg(Prnp-ATXN7*24Q)6129Als transgene insertion 6129, Albert R La Spada

Primary Identifier  MGI:2183506 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Prnp-ATXN7*24Q)6129Als
Inheritance Mode  Not Specified Strain of Origin  (C57BL/6J x C3H/HeJ)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The coding region of human SCA7, containing 24 CAG repeats, was inserted into a murine prion protein promoter (MoPrP) construct. Expression was targeted to the outer nuclear layer, the inner nuclear layer, and the ganglion cell layer of the retina.
  • mutations:
  • Insertion
  • synonyms:
  • PrP-SCA7-c24Q,
  • Tg(SCA7)c24QAls,
  • Tg(SCA7)c24QAls,
  • PrP-SCA7-c24Q
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele