| Primary Identifier | MGI:2183740 | Allele Type | Targeted |
| Gene | Lat | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Tyrosine to phenylalanine mutations were introduced at positions identified as being critical for the binding of signaling molecules (136, 175, 195, and 235) via site-directed mutagenesis. A floxed neomycin selection cassette was inserted downstream of the coding region. Mice carrying this allele were bred with transgenic mice expressing cre recombinase via the EIIa promoter to generate Lattm2.1Lov. |
