Primary Identifier | MGI:2183630 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Itgb4 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The insertion of a neomycin selection cassette deleted sequence extending from 115 base pairs downstream of the start codon through intron 3. The absence of normal transcript in homozygous mutant mice was determined via RT-PCR analysis. While truncated transcript was detected, immunoblot analysis showed an absence of protein. |