Primary Identifier | MGI:2183321 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence, Null/knockout | Gene | Cebpa |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A Cebpb knockin was generated by replacing the entire coding region of the Cebpa locus with the Cebpb coding region. A floxed neomycin selection cassette was inserted downstream of the stop codon. Homozygous mutant mice were bred with transgenic mice expressing cre recombinase, driven by the EIIa promoter, to generate mice carrying Cebpatm1.1(Cebpb)Ylee. |