Primary Identifier | MGI:2183431 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pkd1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacement of exons 2-5 and part of exon 6 with a neomycin resistance cassette via homologous recombination. The gene targeting even results in a frameshift. Absence of gene expression in E12.5 embyros was confirmed by Western blot analysis. |